Chip28 protein
WebThese studies demonstrated: (i) CHIP28 water channel activity is retained despite substitution of individual cysteines with serine; (ii) cysteine 189 is the Hg(2+)-sensitive … WebProtein-coding gene in the species Homo sapiens AQP1 Available structures PDB Ortholog search: PDBeRCSB List of PDB id codes 4CSK, 1FQY, 1H6I, 1IH5 Identifiers Aliases AQP1, AQP-CHIP, CHIP28, CO, …
Chip28 protein
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WebJan 5, 1993 · Molecular identification of CHIP28 protein as the membrane water channel was first accomplished by measurement of osmotic swelling of Xenopus oocytes injected with CHIP28 RNA (Preston, G. M ... WebWater channels provide the plasma membranes of red cells and renal proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Molecular identification of CHIP28 protein as the membrane water channel was first accomplished by measurement of osmotic swelling of Xenopus oocytes injected with …
WebIn 1992 Peter Agre conducted an elegant experiment in which he kept, in water, frog oocytes into which he had introduced a membrane protein called CHIP28. After some minutes … WebComparisons between the amount of CHIP28 RNA injected, osmotic water perme- ability, and number of copies of CHIP28 protein expressed in Xenopus oocytes. After 72 hours, control-injected oocytes and oocytes injected with 0.1 to 10 ng of CHIP28 RNA were studied for osmotic swelling at 22°C.
WebLIN28A. LIN28A (previously LIN28 ), originally found in Caenorhabditis elegans, encodes an RNA-binding protein [protein lin-28 homolog A (Lin-28A)] that has been characterized … WebApr 1, 1992 · The CHIP28 protein is an abundant integral membrane protein in mammalian RBCs and renal proximal tubules and belongs to a family of membrane proteins with unknown functions. Oocytes from Xenopus laevis microinjected with in vitro-transcribed CHIP28 RNA exhibited increased osmotic water permeability; this was reversibly …
WebThe magnitude of CHIP28-mediated water flux (11.7 X 10-14 cm3/s per CHIP28) corresponds to the known Pf of intact RBCs. These results demonstrate that CHIP28 …
WebJan 2, 1993 · CHIP28 comprised 3.8% of isolated proximal tubule brush border protein. Except for the first few cells of the S1 segment, CHIP28 was immunolocalized throughout the convoluted and straight proximal tubules where it was observed in the microvilli of the apical brush border and in basolateral membranes. how to slow a video downnovamed orthopedisch rugkussenWebThe same protein was purified by chance by Agre group in Baltimore, USA, in 1988, who called in 1991 the protein CHIP28 (CHannel forming Integral membrane Protein of 28 kDa), suggesting that it may play a role in linkage of the membrane skeleton to the lipid bilayer. In 1992 the Agre group identified CHIP28's water transport property. novamed surgery center columbusWeb(Figure omitted) The CHIP28 protein is related to the major intrinsic protein from bovine lens, MIP26, a channel through which lens fiber cells may absorb interstitial fluid (14). … how to slow a song downWebChannel forming integral protein of 28 kD (CHIP28) functions as a water channel in erythrocytes, kidney proximal tubule and thin descending limb of Henle. CHIP28 morphology was examined by freeze-fracture EM in proteoliposomes reconstituted with purified CHIP28, CHO cells stably transfected with CHI … how to slow a time lapse videoWebJan 1, 1993 · Abstract. CHIP28 is an integral membrane protein that has been identified as the erythrocyte water channel and that is also expressed in the kidney. Antibodies against erythrocyte CHIP28 were used ... novamed surgery center chicago north shoreWebCHIP28 is found in basolateral and apical plasma membranes of kidney proximal tubules and thin descending limbs of Henle, whereas WCH-CD is apically located in collecting duct principal cells. So far, the putative water channel that may be responsible for the high constitutive permeability of principal cell basolateral membranes has not been ... novamed surgery center chicago il