Cisplatin cervical cancer weekly

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August undefined, 2024

WebAug 19, 2024 · Since the beginning, cisplatin was used as concurrent chemotherapeutic agent in carcinoma cervix, but due to its toxicities such as nephrotoxicity, ototoxicity, nausea, vomiting, and severe electrolyte imbalance, sometimes, the treatment has to stop in between and also aggressive hydration and diuresis is to be needed with cisplatin, … WebMethods: This retrospective analysis included women with locally advanced cervical cancer treated with NACT-CCRT between September 2011 and September 2014. Neoadjuvant chemotherapy included paclitaxel plus cisplatin (TP group; 62 patients) or paclitaxel plus loplatin (TL group; 58 patients), which were administered three weekly, and cisplatin ...

Adding Atezolizumab to Cisplatin and Radiotherapy for Node …

WebFeb 21, 2024 · Efficacy. In the frame of conventionally fractionated radiotherapy, no statistically significant difference in overall survival was observed between low-dose weekly and high-dose three-weekly … WebPatients were randomly assigned to receive one of three chemotherapy regimens: 40 mg of cisplatin per square meter of body-surface area per week for six weeks (group 1); 50 … literary london society

Comparison of two high dose rate intracavitary brachytherapy …

WebNov 11, 2024 · Kim YS, Shin SS, Nam JH, et al. Prospective randomized comparison of monthly fluorouracil and cisplatin versus weekly cisplatin concurrent with pelvic … WebApr 7, 2024 · The recommended dose of cisplatin-based chemotherapy regimens for CCRT is 30‒40 mg/m 2 per week [ 14 ]. The overall time of radiotherapy usually lasts 6–8 weeks, and whether cisplatin chemotherapy needs six to eight cycles remains unclear. Currently, studies on this topic are limited. WebCisplatin is a chemotherapy drug used to treat testicular, ovarian, bladder, head and neck, lung and cervical cancer. It may also be used to treat other cancers. It is best to read … literary lovers box set

Improvement in radiation techniques for locally advanced cervical ...

Concurrent weekly cisplatin and radiotherapy in routine

WebAs a second-generation platinum derivative, nedaplatin has been demonstrated to be equivalent to or have superior antineoplasic activity to cisplatin with less toxicity in cervical cancer. 24–26 The majority of our patient population was administered with weekly nedaplatin. Grade 3 acute toxicities were observed in only 4 patients (14.3% ... WebApr 10, 2024 · and the Thai Cooperative Group, compared weekly cisplatin cancer therapy to every-3-week chemotherapy for locally advanced cervical cancer. In addition, the concurrent chemoradiotherapy plus brachytherapy with carboplatin and paclitaxel in patients with locally advanced cervical cancer (OUTBACK) trial [NCT01414608]8 was literary luminary crosswordWebNational Center for Biotechnology Information literary love letters and other stories

"WebCisplatin was given intravenously once a week at a dose of 40 mg per square meter of body-surface area, with the total dose not to exceed 70 mg per week. A maximum of six doses of cisplatin was... " - Cisplatin cervical cancer weekly

Cisplatin cervical cancer weekly

Cisplatin, Radiation, and Adjuvant Hysterectomy Compared with …

WebPlatinum-based combination chemotherapy vs. weekly cisplatin during adjuvant CCRT in early cervical cancer with pelvic LN metastasis We found that platinum-based combination chemotherapy during adjuvant CCRT after surgery promoted better survival than a weekly cisplatin regimen in ECC patients with pelvic LN metastasis. WebCisplatin is called the “penicillin of cancer” because it is used so widely and it was the first big chemotherapy drug. Cisplatin also plays an interesting role in the history of …

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WebDec 8, 2024 · Chemoradiation with cisplatin 100 mg/m 2 given once every 3 weeks is the standard of care in locally advanced head and neck squamous cell cancer (LAHNSCC). Increasingly, low-dose once-a-week … WebJul 19, 2016 · Carboplatin yielded comparable results to cisplatin in concurrent chemo-radiation for locally advanced cervical cancer. In addition, carboplatin was associated with a better compliance rate and was associated with less of anemia, neutropenia and nephrotoxicity. ... CCRT with weekly cisplatin at a dose of 40 mg/m 2 or weekly …

WebApr 8, 2024 · Sixty-nine patients with cervical cancer treated with curative or postoperative adjuvant therapy received weekly cisplatin concurrent chemotherapy (CCT) and intensity-modulated radiation therapy (IMRT). The whole pelvic bone marrow (PBM) was delineated and divided into three subsites: ilium (IL), lower pelvis (LP), and lumbosacral spine (LS). WebApr 8, 2024 · Objective To evaluate the impact of bone marrow (BM) irradiation dose on acute haematologic toxicity (HT) in concurrent chemoradiotherapy for cervical cancer. …

WebMethods: All patients were randomly assigned (half in each group)to receive weekly cisplatin at a dose of 40 mg/m2 compared to 20 mg/m2, concurrent with … WebOct 11, 2024 · Thirty-nine patients with advanced, recurrent, or persistent cervical cancer were treated with a combination of cisplatin and topotecan as second-line chemotherapy between January 2000 and December 2015. The median patient age was 47 years (range, 32–73 years). The distribution of the histological subtypes was as follows: …

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WebNov 1, 2004 · Purpose: To evaluate patient compliance and acute toxicity accompanying concurrent weekly cisplatin and radiotherapy (RT) in the routine management of … importance of the day 22 augustWebJan 10, 2024 · Background Currently, the standard treatment for locally advanced cervical cancer is concurrent chemoradiation (CCRT). The effect of neoadjuvant chemotherapy in advanced cervical cancer is controversial. Studies have shown that the addition of a weekly regimen of neoadjuvant chemotherapy (NACT) followed by CCRT may be … literary london mapWebMethods: This retrospective analysis included women with locally advanced cervical cancer treated with NACT-CCRT between September 2011 and September 2014. Neoadjuvant … literary luminaryWebA multi-institutional observational study on the effects of three-dimensional radiotherapy and weekly 40-mg/m2 cisplatin on postoperative uterine cervical cancer patients with high-risk prognostic factors literary london toursWebDay 1:Carboplatin AUC 2 IV over 30 minutes. Repeat cycle weekly for 6 weeks with concurrent radiation. Cisplatin3,a,bDay 1:Cisplatin 40mg/m2IV over 60 minutes. Repeat … importance of the day feb 23WebJul 18, 2024 · Cervical Cancer† Invasive Cervical Cancer† IV Monotherapy: 40 mg/m 2 once weekly has been administered concurrently with radiation therapy up to a maximum of 6 doses. Combination chemotherapy (e.g., with fluorouracil): 50–75 mg/m 2 has been administered concurrently with radiation therapy according to various dosage schedules. importance of the day 22 novemberWebApr 10, 2024 · The OUTBACK trial8 randomized patients with locally advanced cervical cancer to standard concurrent chemoradiotherapy plus brachytherapy with weekly … importance of the day 9 january