WebAug 12, 2011 · Many standard approaches from the literature can be visualized using Bonferroni-based graphical test procedures, including the weighted or unweighted Bonferroni–Holm procedure (Holm, 1979 ), fixed sequence tests (Maurer et. al, 1995; Westfall and Krishen, 2001 ), fallback procedures (Wiens, 2003 ), and gatekeeping … WebOffice of Communications, Division of Drug Information Center for Drug Evaluation and Research Food and Drug Administration 10001 New Hampshire Ave., Hillandale Bldg., …
University of North Carolina at Chapel Hill
WebFeb 1, 2008 · Huque and Alosh [8] developed a flexible fixed-sequence (FFS) testing method to improve the BFS approach by considering correlation among endpoints, which can be viewed as a parametric... WebFeb 1, 2008 · On the other hand, a fixed sequence (FS) approach allows testing of each of the k null hypotheses at the same significance level of α without any adjustment, as long … northern lights images background
A fixed sequence Bonferroni procedure for testing multiple …
WebFeb 15, 2009 · For clinical trials with multiple treatment arms or endpoints a variety of sequentially rejective, weighted Bonferroni-type tests have been proposed, such as gatekeeping procedures, fixed sequence tests, and fallback procedures. They allow to map the difference in importance as well as the relations … WebJan 5, 2024 · We first consider a conventional fixed sequence method that stops testing once an acceptance occurs, and develop such a method controlling the FDR under both … Webondary endpoints, the endpoints may be arranged in a sequence. In this case, each endpoint defines a family and serves as a serial gatekeeper for the next family in the sequence. Multiple testing procedures that control the FWER in problems with serial gatekeepers are discussed in Section 5.3. 5.2.2 Clinical trials with parallel gatekeepers northern lights image