WebGSTCD (glutathione S-transferase, C-terminal domain containing) is a 633 amino acid protein belonging to the GSTCD family and contains one GST C-terminal domain. The gene encoding GSTCD maps to human chromosome 4, which represents approximately 6 % of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, … WebVariant 2 encodes a deduced 546-amino acid protein that lacks amino acids 55 to 141 of the full-length protein. GSTCD shares homology with glutatione S-transferases (GSTs; see 138359 ), but it lacks functional domains important for GST activity. Database analysis revealed ubiquitous GSTCD expression.

Glutathione S-Transferase SpringerLink

WebHere, we capitalize on our findings that C-termin... More Epidermal growth factor receptor tyrosine kinase substrate 15 (Eps15) homology (EH)-domain proteins can be divided into two classes: those with an N-terminal EH-domain(s), and the C-terminal Eps15 homology domain-containing proteins (EHDs). WebApr 1, 1999 · Glutathione S-transferase belongs to the system of ... The encoded proteins differ only for three amino acids all of them included in the C-terminal domain of the enzymes (R89P, E117K, I ... rama ontario works

Glutathione S-Transferase - an overview ScienceDirect Topics

WebJan 1, 2024 · Glutathione S-Transferase, Fig. 1. GSTP and GSTM act as regulators of cellular signaling. GSTP interacts and inhibits JNK activity by sequestering JNK/c-Jun, whereas GSTM binds MEKK1 and ASK1 directly. These protein–protein interactions negatively regulate oxidative stress-induced cell growth, differentiation, and apoptosis. WebThe Schistosoma juponicum 26 kDa glutathione S-transferase (sj26GST) consists of the N-terminal domain (N-domain), containing three alpha-helices (named H1-H3) and four … WebKeywords: Acanthamoeba; glutathione S-transferase; encystation; cyst 1. Introduction Acanthamoeba is well known to cause infections in the central nervous system [1,2] rama of eye