Pubmed statins

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August undefined, 2024

WebApr 11, 2024 · Statins are a class of medicines routinely prescribed to lower cholesterol and are known to prevent cardiovascular disease in those at risk in the general population. It was not clear if statins would have the same effect in people living with HIV and who have premature cardiovascular disease despite having low-to-moderate traditional risk. WebFeb 4, 2024 · Statins are important drugs that reduce cardiovascular risk factors and should be prescribed to appropriate patients with these risk factors but some of this population …

Full article: Statins and muscle pain - Taylor & Francis

WebJul 14, 2024 · A potential concern with statins and COVID-19 is that statins may increase the expression of ACE2 9 —the membrane receptor that allows SARS-CoV-2 to gain entry into … WebJul 27, 2024 · To reflect changes in the use of statin over time (e.g., new initiation or discontinuation, change to other statins), statin use was defined as a time-varying … selling a house in pa

Statin Use for the Primary Prevention of Cardiovascular Disease

WebStatins are drugs of known and undisputed efficacy in the treatment of hypercholesterolemia, usually well tolerated by most patients. In some cases treatment … WebStatins have antiathero … The beneficial effects of statins are the result of their capacity to reduce cholesterol biosyntesis, mainly in the liver, where they are selectively distributed, … WebSep 27, 2024 · reported that patients with Graves' disease receiving statin treatment for hypercholesterolaemia have a reduced risk for the occurrence of Graves' orbitopathy. Of note, in the American study the use of non-statin cholesterol lowering drugs was not associated with a reduced risk of orbitopathy, suggesting that the protective effect of … selling a house in portugal

Remembering Statins: Do Statins Have Adverse Cognitive Effects?

Statins and Neuropathic Pain: A Narrative Review SpringerLink

WebThe use of statins has been associated with decreased cardiovascular mortality. Studies of overall mortality have been somewhat less conclusive (1), but a retrospective cohort study in the Veterans Administration population also using propensity scoring showed a hazard ratio favoring statin use of 0.75 (95% CI, 0.74-0.76) for all-cause mortality, and 0.80 (95% CI, … WebLowering LDL cholesterol with statin therapy in people considered at low risk of atherosclerotic cardiovascular disease also lowers the risk of major vascular events, and … selling a house in glendaleWebDec 1, 2024 · Importance: Statin therapy has been associated with increased insulin resistance; however, its clinical implications for diabetes control among patients with … selling a house in maricopa

"WebHowever, results of individual studies were inconsistent, with 1 large trial (JUPITER) showing increased diabetes risk. 27 This could be due to JUPITER being the only trial to use high-potency statin therapy; other analyses that included trials of statins for secondary prevention suggest an association between intensity of statin dose and risk of incident … " - Pubmed statins

Pubmed statins

Statins stimulate atherosclerosis and heart failure

WebApr 13, 2013 · During 1.2 million person-years of follow-up, there were 13,455 cases of type 2 diabetes and 8,932 deaths. Statin initiation was associated with increased risk of type 2 diabetes. The hazard ratio (95% CI) of diabetes was 1.45 (1.39–1.50) before adjusting for potential confounders and 1.14 (1.10–1.19) after adjustment. WebJul 16, 2016 · With so many people eligible for treatment, even rare adverse effects become important. In 2012, the U.S. Food and Drug Administration (FDA) issued a statement regarding rare postmarketing reports of ill-defined cognitive impairment associated with statin use that was reversible upon statin discontinuation ().This has led many people, …

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WebMar 18, 2024 · The concerns of Rory Collins and colleagues in their recent comprehensive Review1 addressing possible under use of statins, are well received. However, more than … WebMar 4, 2024 · Administration of statins to lower elevated levels of low-density lipoprotein (LDL) cholesterol is the cornerstone of contemporary therapy to reduce the risk of major …

WebNov 5, 2024 · The oral route of drug administration is the most common and convenient route for dosing statin drugs, and, in fact, most medications, because of ease of drug delivery, patient compliance, and cost-effectiveness. However, the oral administration of statin drugs has disadvantages such as hepatic first-pass metabolism and degradation … WebMar 6, 2024 · Among patients receiving contemporary statins, inflammation assessed by high-sensitivity CRP was a stronger predictor for risk of future cardiovascular events and …

WebStatins are 3-hydroxy-3-methyglutaryl coenzyme A (HMG-CoA) reductase inhibitors, which are prescribed extensively for cholesterol lowering in the primary and secondary … WebHowever, results of individual studies were inconsistent, with 1 large trial (JUPITER) showing increased diabetes risk. 27 This could be due to JUPITER being the only trial to use high …

WebApr 14, 2024 · A. A. Black patients have 71% greater odds of cardiotoxicity following cancer treatment compared with White patients, according to a new meta-analysis presented at ACC's Advancing the Cardiovascular Care of the Oncology Patient 2024 conference taking place April 14-16 in Washington, DC, and virtually. Wondewossen Gebeyehu, BSc, et al., …

WebMyopathy is the most frequent side effect of statins and in some cases may have a form of severe rhabdomyolysis. Less common adverse effects include hepatotoxicity, peripheral … selling a house in nsw processWebNational Center for Biotechnology Information selling a house in nj taxWebAug 17, 2024 · Statins have been recommended by several guidelines as the primary prevention medication for cardiovascular diseases. However, the benefits of statin therapy for cerebral small vessel disease (CSVD), particularly in adults ≥75 years of age, have not been fully evaluated. We analyzed the data from a prospective population-based cohort … selling a house in reginaWebThe key to the better detection and management of FH is early diagnosis, followed by an appropriate ongoing heart-healthy diet and appropriate medications (usually statins) from 8–10 years of age. 3 Children with FH managed this way can expect to live a normal lifespan and avoid premature ASCVD. 3,4 The disease begins in childhood, not in adulthood. 1,3–5 … selling a house in probateWebWe conclude that statins contribute to macrophage-bactericidal activity against Mycobacterium bovis, M. leprae, and M. tuberculosis. It is likely that the association of … selling a house in phoenixWebFeb 22, 2024 · 1. Introduction. Statin therapy is recommended both for primary and secondary prevention of cardiovascular disease [Citation 1, Citation 2].Statins have been and remain among the most frequently prescribed drugs in the world [Citation 3].Their mechanism of action is the reversible inhibition of 3-hydroxy-3-methylglutaryl coenzyme A … selling a house in marylandWebMar 6, 2024 · Among patients receiving contemporary statins, inflammation assessed by high-sensitivity CRP was a stronger predictor for risk of future cardiovascular events and death than cholesterol assessed by LDLC. These data have implications for the selection of adjunctive treatments beyond statin therapy and suggest that combined use of … selling a house in vermont