Webb6 feb. 2024 · By using either sorted or transfected lung fibroblasts, ... Thy-1 deficient (Thy1−/−) mice displayed persistence of myofibroblasts in the resolution phase of bleomycin-induced fibrosis, ... Webb23 feb. 2024 · Low expression of TNFRSF11B in CD34 – THY1 – fibroblasts and CD34 – THY1 + fibroblasts was confirmed by direct protein measurement from supernatant of …
Current perspectives on the role of orbital fibroblasts in the ...
Webb20 maj 2024 · Fibroblast-like synoviocytes (FLSs) exhibit critical immunomodulatory functions through secretion of inflammatory cytokines and through direct interactions with several synovial-infiltrated immune cell types (1,2). ... FAPα + THY1 − fibroblasts are responsible for bone and cartilage damage, ... Webb1 apr. 2024 · FAPα+ Thy1 - FLS were mainly located in the lining layer, expressing high levels of osteoclast activity inducers (CCL9 and TNFS11) and MMPs involved in cartilage degradation (MMP3, MMP9, and MMP13), thus mediating bone and … flights from sacramento to fiji
THY1 (Thy-1 cell surface antigen) - atlasgeneticsoncology.org
Webb27 feb. 2024 · In lung fibroblasts, a colocalization of Thy-1 with Fas (CD95) in lipid rafts promotes lung fibroblast susceptibility to apoptosis . Zhou et al . reported that Thy-1 interacts with integrin αvβ5 on lung fibroblasts and prevents contraction-induced, integrin αvβ5–dependent, latent TGF-β1 activation and myofibroblast differentiation. Webb25 juli 2024 · Because Thy-1 (CD90) marks CAFs that promote tumor cell invasion in a murine model of Kras G12D -driven lung adenocarcinoma (Kras LA1 ), here we postulated that human lung adenocarcinomas containing Thy-1 + CAFs have a worse prognosis. We first examined the location of Thy-1 + CAFs within human lung adenocarcinomas. Webb22 mars 2024 · Thy1 has been suggested as a marker of portal (myo)fibroblasts, yet selective isolation and an in-depth characterization of these Thy1-expressing cells in mouse liver have not been performed. 24 Thus, we aimed to evaluate the relationship of our Thy1 MCs to portal (myo)fibroblasts, taking advantage of Thy1 as a surface antigen. flights from sacramento to ocala florida